Prison Break Season 4 was planned to air 22 episodes and will have a two-hour premiere on September 1, 2008 in the United States and September 2, 2008 in the United Kingdom via Sky 1. This season, instead of a break out, they will be making a break in.
As the fourth season opens, Michael is in Los Angeles, looking to even the score with Gretchen for Sara's death, while Gretchen, Whistler and Mahone go about Company business. Sara Tancredi, who was believed to have been killed in season 3, will be making a return as a regular cast member in season 4. The first episode was titled "Scyla"